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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX58
All Species:
19.7
Human Site:
S658
Identified Species:
43.33
UniProt:
Q96C10
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C10
NP_077024.2
678
76613
S658
K
W
S
R
V
P
F
S
V
P
D
F
D
F
L
Chimpanzee
Pan troglodytes
XP_001167051
678
76609
S658
K
W
S
R
V
P
F
S
V
P
D
F
D
F
L
Rhesus Macaque
Macaca mulatta
XP_001108799
678
76729
S658
K
W
S
R
V
P
F
S
V
P
D
F
D
F
L
Dog
Lupus familis
XP_850033
678
76952
P658
K
W
S
R
V
P
F
P
V
P
D
F
D
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J87
678
76708
S658
K
W
S
R
V
P
F
S
I
P
V
F
D
I
L
Rat
Rattus norvegicus
NP_001092258
678
76894
S658
K
W
S
R
V
P
F
S
V
P
D
F
D
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
I882
E
S
F
V
V
E
D
I
F
T
G
A
Q
H
V
Chicken
Gallus gallus
XP_422031
1285
144686
L1266
I
F
K
K
W
G
E
L
P
I
I
F
P
D
F
Frog
Xenopus laevis
NP_001085915
682
79226
P660
R
W
K
D
V
P
F
P
V
D
E
L
N
Y
V
Zebra Danio
Brachydanio rerio
XP_694124
738
84421
S713
K
W
R
E
L
S
I
S
F
P
A
F
D
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176480
823
93488
F700
K
K
W
T
D
V
P
F
A
I
R
S
I
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
84.6
N.A.
78.9
79.1
N.A.
26.9
23.7
51.1
38.8
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.4
97.9
91.4
N.A.
87.6
87.7
N.A.
43.9
35.8
67.4
57.1
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
100
86.6
N.A.
80
93.3
N.A.
6.6
6.6
33.3
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
20
20
66.6
53.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
10
0
0
10
46
0
64
19
0
% D
% Glu:
10
0
0
10
0
10
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
64
10
19
0
0
73
0
28
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
10
10
10
19
10
0
10
19
0
% I
% Lys:
73
10
19
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
64
10
19
10
64
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
10
55
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
55
0
0
10
0
55
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% T
% Val:
0
0
0
10
73
10
0
0
55
0
10
0
0
0
19
% V
% Trp:
0
73
10
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _